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The simple answer is: not really...but we have a great compromise!
Our best option for seeing 'just the Sistine Chapel' is our Vatican Gardens & Sistine Chapel Tour. This tour allows you to start with the beautiful Vatican Gardens - not visited by the overwhelming majority of tourists, absolutely breath-taking, and much, much less crowded than the Vatican Museums. Then, through a special door, you enter the Sistine Chapel directly. This means you will skip 99% of crowds in the museums, see the gardens (hidden in plain site, but overlooked by most tourists) and then enter the stunning Sistine Chapel with your guide. After the Chapel, you'll head to stunning St. Peter's Basilica before ending your tour in St. Peter's Square. So, it's not the Sistine Chapel all by itself, but a great alternative that will leave you with unique memories for a lifetime!